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Population Pharmacokinetics of Intravenous Amoxicillin Combined With Clavulanic Acid in Healthy and Critically Ill Dogs

Background: Data regarding antimicrobial pharmacokinetics (PK) in critically ill dogs are lacking and likely differ from those of healthy dogs. The aim of this work is to describe a population PK model for intravenous (IV) amoxicillin–clavulanic acid (AMC) in both healthy and sick dogs and to simula...

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Detalles Bibliográficos
Autores principales: Vegas Cómitre, Maria D., Cortellini, Stefano, Cherlet, Marc, Devreese, Mathias, Roques, Beatrice B., Bousquet-Melou, Alain, Toutain, Pierre-Louis, Pelligand, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636140/
https://www.ncbi.nlm.nih.gov/pubmed/34869739
http://dx.doi.org/10.3389/fvets.2021.770202