Randomised clinical trials in critical care: past, present and future

Randomised clinical trials (RCTs) are the gold standard for providing unbiased evidence of intervention effects. Here, we provide an overview of the history of RCTs and discuss the major challenges and limitations of current critical care RCTs, including overly optimistic effect sizes; unnuanced con...

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Detalles Bibliográficos
Autores principales: Granholm, Anders, Alhazzani, Waleed, Derde, Lennie P. G., Angus, Derek C., Zampieri, Fernando G., Hammond, Naomi E., Sweeney, Rob Mac, Myatra, Sheila N., Azoulay, Elie, Rowan, Kathryn, Young, Paul J., Perner, Anders, Møller, Morten Hylander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636283/
https://www.ncbi.nlm.nih.gov/pubmed/34853905
http://dx.doi.org/10.1007/s00134-021-06587-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636283/
https://www.ncbi.nlm.nih.gov/pubmed/34853905
http://dx.doi.org/10.1007/s00134-021-06587-9

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