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People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden

Despite extensive analyses, there remains an urgent need to delineate immune cell states that contribute to mortality in people critically ill with COVID-19. Here, we present high-dimensional profiling of blood and respiratory samples from people with severe COVID-19 to examine the association betwe...

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Detalles Bibliográficos
Autores principales: Cillo, Anthony R., Somasundaram, Ashwin, Shan, Feng, Cardello, Carly, Workman, Creg J., Kitsios, Georgios D., Ruffin, Ayana T., Kunning, Sheryl, Lampenfeld, Caleb, Onkar, Sayali, Grebinoski, Stephanie, Deshmukh, Gaurav, Methe, Barbara, Liu, Chang, Nambulli, Sham, Andrews, Lawrence P., Duprex, W. Paul, Joglekar, Alok V., Benos, Panayiotis V., Ray, Prabir, Ray, Anuradha, McVerry, Bryan J., Zhang, Yingze, Lee, Janet S., Das, Jishnu, Singh, Harinder, Morris, Alison, Bruno, Tullia C., Vignali, Dario A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636386/
https://www.ncbi.nlm.nih.gov/pubmed/34873589
http://dx.doi.org/10.1016/j.xcrm.2021.100476