Cargando…
People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden
Despite extensive analyses, there remains an urgent need to delineate immune cell states that contribute to mortality in people critically ill with COVID-19. Here, we present high-dimensional profiling of blood and respiratory samples from people with severe COVID-19 to examine the association betwe...
Autores principales: | Cillo, Anthony R., Somasundaram, Ashwin, Shan, Feng, Cardello, Carly, Workman, Creg J., Kitsios, Georgios D., Ruffin, Ayana T., Kunning, Sheryl, Lampenfeld, Caleb, Onkar, Sayali, Grebinoski, Stephanie, Deshmukh, Gaurav, Methe, Barbara, Liu, Chang, Nambulli, Sham, Andrews, Lawrence P., Duprex, W. Paul, Joglekar, Alok V., Benos, Panayiotis V., Ray, Prabir, Ray, Anuradha, McVerry, Bryan J., Zhang, Yingze, Lee, Janet S., Das, Jishnu, Singh, Harinder, Morris, Alison, Bruno, Tullia C., Vignali, Dario A.A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636386/ https://www.ncbi.nlm.nih.gov/pubmed/34873589 http://dx.doi.org/10.1016/j.xcrm.2021.100476 |
Ejemplares similares
-
Bifurcated monocyte states are predictive of mortality in severe COVID-19
por: Cillo, Anthony R., et al.
Publicado: (2021) -
COVID-19 versus Non–COVID-19 Acute Respiratory Distress Syndrome: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes
por: Bain, William, et al.
Publicado: (2021) -
Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19
por: Peddireddy, Sai Preetham, et al.
Publicado: (2022) -
Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study
por: Hensley, Matthew K, et al.
Publicado: (2021) -
Distinct profiles of host responses between plasma and lower respiratory tract during acute respiratory failure
por: Kitsios, Georgios D., et al.
Publicado: (2023)