Conserved Induction of Distinct Antiviral Signalling Kinetics by Primate Interferon Lambda 4 Proteins

Interferon lambdas (IFNλ) (also known as type III IFNs) are critical cytokines that combat infection predominantly at barrier tissues, such as the lung, liver, and gastrointestinal tract. Humans have four IFNλs (1–4), where IFNλ1–3 show ~80%–95% homology, and IFNλ4 is the most divergent displaying o...

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Detalles Bibliográficos
Autores principales: Guo, Cuncai, Reuss, Dorothee, Coey, Jonathon D., Sukumar, Swathi, Lang, Benjamin, McLauchlan, John, Boulant, Steeve, Stanifer, Megan L., Bamford, Connor G. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636442/
https://www.ncbi.nlm.nih.gov/pubmed/34868037
http://dx.doi.org/10.3389/fimmu.2021.772588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636442/
https://www.ncbi.nlm.nih.gov/pubmed/34868037
http://dx.doi.org/10.3389/fimmu.2021.772588

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