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Histone H2A Nuclear/Cytoplasmic Trafficking Is Essential for Negative Regulation of Antiviral Immune Response and Lysosomal Degradation of TBK1 and IRF3

Histone H2A is a nuclear molecule tightly associated in the form of the nucleosome. Our previous studies have demonstrated the antibacterial property of piscine H2A variants against gram-negative bacteria Edwardsiella piscicida and Gram-positive bacteria Streptococcus agalactiae. In this study, we s...

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Detalles Bibliográficos
Autores principales: Wu, Xiao Man, Fang, Hong, Zhang, Jie, Bi, Yong Hong, Chang, Ming Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636446/
https://www.ncbi.nlm.nih.gov/pubmed/34868031
http://dx.doi.org/10.3389/fimmu.2021.771277