Cargando…
Histone H2A Nuclear/Cytoplasmic Trafficking Is Essential for Negative Regulation of Antiviral Immune Response and Lysosomal Degradation of TBK1 and IRF3
Histone H2A is a nuclear molecule tightly associated in the form of the nucleosome. Our previous studies have demonstrated the antibacterial property of piscine H2A variants against gram-negative bacteria Edwardsiella piscicida and Gram-positive bacteria Streptococcus agalactiae. In this study, we s...
Autores principales: | Wu, Xiao Man, Fang, Hong, Zhang, Jie, Bi, Yong Hong, Chang, Ming Xian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636446/ https://www.ncbi.nlm.nih.gov/pubmed/34868031 http://dx.doi.org/10.3389/fimmu.2021.771277 |
Ejemplares similares
-
A Novel Transcript Isoform of TBK1 Negatively Regulates Type I IFN Production by Promoting Proteasomal Degradation of TBK1 and Lysosomal Degradation of IRF3
por: Zhang, Jie, et al.
Publicado: (2020) -
TANK-Binding Kinase 1 (TBK1) Isoforms Negatively Regulate Type I Interferon Induction by Inhibiting TBK1-IRF3 Interaction and IRF3 Phosphorylation
por: Hu, Yi Wei, et al.
Publicado: (2018) -
PGAM5-MAVS interaction regulates TBK1/ IRF3 dependent antiviral responses
por: Yu, Yu-qiang, et al.
Publicado: (2020) -
Histone deacetylase 3 promotes innate antiviral immunity through deacetylation of TBK1
por: Tang, Jie-lin, et al.
Publicado: (2020) -
Negative regulation of TBK1‐mediated antiviral immunity
por: Zhao, Wei
Publicado: (2013)