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Characterization of a G-quadruplex from hepatitis B virus and its stabilization by binding TMPyP4, BRACO19 and PhenDC3

Specific guanine rich nucleic acid sequences can form non-canonical structures, like the four stranded G-quadruplex (GQ). We studied the GQ-forming sequence (named HepB) found in the genome of the hepatitis B virus. Fluorescence-, infrared- and CD-spectroscopy were used. HepB shows a hybrid form in...

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Detalles Bibliográficos
Autores principales: Molnár, Orsolya Réka, Végh, András, Somkuti, Judit, Smeller, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636512/
https://www.ncbi.nlm.nih.gov/pubmed/34853392
http://dx.doi.org/10.1038/s41598-021-02689-y