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Therapeutic potential of TRPM8 antagonists in prostate cancer

Transient receptor potential melastatin-8 (TRPM8) represents an emerging target in prostate cancer, although its mechanism of action remains unclear. Here, we have characterized and investigated the effects of TRPM8 modulators in prostate cancer aggressiveness disclosing the molecular mechanism unde...

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Detalles Bibliográficos
Autores principales: Di Donato, Marzia, Ostacolo, Carmine, Giovannelli, Pia, Di Sarno, Veronica, Monterrey, Isabel M. Gomez, Campiglia, Pietro, Migliaccio, Antimo, Bertamino, Alessia, Castoria, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636514/
https://www.ncbi.nlm.nih.gov/pubmed/34853378
http://dx.doi.org/10.1038/s41598-021-02675-4