Role of Amino Acid Arginine and Nitric Oxide in Mechanisms of Cytoprotective Effect of Non-Opiate Leu-Enkephalin Analogue In Vitro

Incubation of primary culture of pulmonary fibroblasts with non-opiate analogue of leuenkephalin (NALE; Phe-D-Ala-Gly-Phe-Leu-Arg, 0.1 μM) reduced generation of superoxide anion-radical (by 20.7%) and decreased the number of p53(+) cells (by 40.2%) induced by exposure to H(2)O(2) (60 μM). The cytopr...

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Detalles Bibliográficos
Autores principales: Sazonova, E. N., Lebed’ko, O. A., Pinaeva, O. G., Tsimbalist, N. A., Kupriyanova, D. A., Tarasov, P. K., Malofey, Yu. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636574/
https://www.ncbi.nlm.nih.gov/pubmed/34855076
http://dx.doi.org/10.1007/s10517-021-05374-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636574/
https://www.ncbi.nlm.nih.gov/pubmed/34855076
http://dx.doi.org/10.1007/s10517-021-05374-2

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