Kinetic and structural mechanism for DNA unwinding by a non-hexameric helicase

UvrD, a model for non-hexameric Superfamily 1 helicases, utilizes ATP hydrolysis to translocate stepwise along single-stranded DNA and unwind the duplex. Previous estimates of its step size have been indirect, and a consensus on its stepping mechanism is lacking. To dissect the mechanism underlying...

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Detalles Bibliográficos
Autores principales: Carney, Sean P., Ma, Wen, Whitley, Kevin D., Jia, Haifeng, Lohman, Timothy M., Luthey-Schulten, Zaida, Chemla, Yann R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636605/
https://www.ncbi.nlm.nih.gov/pubmed/34853304
http://dx.doi.org/10.1038/s41467-021-27304-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636605/
https://www.ncbi.nlm.nih.gov/pubmed/34853304
http://dx.doi.org/10.1038/s41467-021-27304-6

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