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Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut

Zinc is an essential cofactor for bacterial metabolism, and many Enterobacteriaceae express the zinc transporters ZnuABC and ZupT to acquire this metal in the host. However, the probiotic bacterium Escherichia coli Nissle 1917 (or “Nissle”) exhibits appreciable growth in zinc-limited media even when...

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Detalles Bibliográficos
Autores principales: Behnsen, Judith, Zhi, Hui, Aron, Allegra T., Subramanian, Vivekanandan, Santus, William, Lee, Michael H., Gerner, Romana R., Petras, Daniel, Liu, Janet Z., Green, Keith D., Price, Sarah L., Camacho, Jose, Hillman, Hannah, Tjokrosurjo, Joshua, Montaldo, Nicola P., Hoover, Evelyn M., Treacy-Abarca, Sean, Gilston, Benjamin A., Skaar, Eric P., Chazin, Walter J., Garneau-Tsodikova, Sylvie, Lawrenz, Matthew B., Perry, Robert D., Nuccio, Sean-Paul, Dorrestein, Pieter C., Raffatellu, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636617/
https://www.ncbi.nlm.nih.gov/pubmed/34853318
http://dx.doi.org/10.1038/s41467-021-27297-2