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Tumor evolution selectively inactivates the core microRNA machinery for immune evasion

Cancer cells acquire genetic heterogeneity to escape from immune surveillance during tumor evolution, but a systematic approach to distinguish driver from passenger mutations is lacking. Here we investigate the impact of different immune pressure on tumor clonal dynamics and immune evasion mechanism...

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Detalles Bibliográficos
Autores principales: Song, Tian-Yu, Long, Min, Zhao, Hai-Xin, Zou, Miao-Wen, Fan, Hong-Jie, Liu, Yang, Geng, Chen-Lu, Song, Min-Fang, Liu, Yu-Feng, Chen, Jun-Yi, Yang, Yu-Lin, Zhou, Wen-Rong, Huang, Da-Wei, Peng, Bo, Peng, Zhen-Gang, Cang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636623/
https://www.ncbi.nlm.nih.gov/pubmed/34853298
http://dx.doi.org/10.1038/s41467-021-27331-3