Targeting SYK of monocyte-derived macrophages regulates liver fibrosis via crosstalking with Erk/Hif1α and remodeling liver inflammatory environment

Liver fibrosis is a danger signal indicating a huge risk of liver cancer occurrence, but there is still no effective clinical means to regulate the progress of liver fibrosis. Although a variety of drugs targeting SYK have been developed for tumors and autoimmune diseases, the mechanism and specific...

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Detalles Bibliográficos
Autores principales: Chen, Xuejiao, Wang, Ziyi, Han, Sheng, Wang, Zeng, Zhang, Yu, Li, Xiangdong, Xia, Nan, Yu, Wenjie, Jia, Chenyang, Ni, Yong, Pu, Liyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636632/
https://www.ncbi.nlm.nih.gov/pubmed/34853322
http://dx.doi.org/10.1038/s41419-021-04403-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636632/
https://www.ncbi.nlm.nih.gov/pubmed/34853322
http://dx.doi.org/10.1038/s41419-021-04403-2

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