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Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium

There is evidence that the cystic fibrosis transmembrane conductance regulator (CFTR) anion channel is highly expressed at the apical pole of ciliated cells in human bronchial epithelium (HBE), however recent studies have detected little CFTR mRNA in those cells. To understand this discrepancy we im...

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Detalles Bibliográficos
Autores principales: Sato, Yukiko, Mustafina, Kamila R., Luo, Yishan, Martini, Carolina, Thomas, David Y., Wiseman, Paul W., Hanrahan, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636639/
https://www.ncbi.nlm.nih.gov/pubmed/34853321
http://dx.doi.org/10.1038/s41598-021-02420-x