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ALKBH5-mediated m(6)A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling

Long noncoding RNAs (lncRNAs) are regarded as crucial regulators in tumor progression. Potassium two pore domain channel subfamily K member 15 and WISP2 antisense RNA 1 (KCNK15-AS1) has been confirmed to inhibit the migration and invasion of pancreatic cancer (PC) cells. However, its downstream mech...

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Detalles Bibliográficos
Autores principales: He, Yuan, Yue, HongQin, Cheng, Ying, Ding, Zhilong, Xu, Zhen, Lv, Chunyang, Wang, Zheng, Wang, Jing, Yin, Chenglong, Hao, Huihui, Chen, Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636648/
https://www.ncbi.nlm.nih.gov/pubmed/34853296
http://dx.doi.org/10.1038/s41419-021-04401-4