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In vivo Serial Passaging of Human–Simian Immunodeficiency Virus Clones Identifies Characteristics for Persistent Viral Replication

We previously reported that a human immunodeficiency virus type 1 with a simian immunodeficiency virus vif substitution (HSIV-vif(NL4-3)) could replicate in pigtailed macaques (PTMs), demonstrating that Vif is a species-specific tropism factor of primate lentiviruses. However, infections did not res...

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Detalles Bibliográficos
Autores principales: Thippeshappa, Rajesh, Polacino, Patricia, Chandrasekar, Shaswath S., Truong, Khanghy, Misra, Anisha, Aulicino, Paula C., Hu, Shiu-Lok, Kaushal, Deepak, Kimata, Jason T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636705/
https://www.ncbi.nlm.nih.gov/pubmed/34867922
http://dx.doi.org/10.3389/fmicb.2021.779460