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Drug-peptide supramolecular hydrogel boosting transcorneal permeability and pharmacological activity via ligand-receptor interaction

Boosting transcorneal permeability and pharmacological activity of drug poses a great challenge in the field of ocular drug delivery. In the present study, we propose a drug-peptide supramolecular hydrogel based on anti-inflammatory drug, dexamethasone (Dex), and Arg-Gly-Asp (RGD) motif for boosting...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Deng, Jie, Yu, Ailing, Hu, Yuhan, Jin, Bo, Du, Pengyuan, Zhou, Jianhong, Lei, Lei, Wang, Yuan, Vakal, Serhii, Li, Xingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636707/
https://www.ncbi.nlm.nih.gov/pubmed/34901557
http://dx.doi.org/10.1016/j.bioactmat.2021.09.006