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Computational prediction and validation of specific EmbR binding site on PknH

Tuberculosis drug resistance continues to threaten global health but the underline molecular mechanisms are not clear. Ethambutol (EMB), one of the well-known first - line drugs in tuberculosis treatment is, unfortunately, not free from drug resistance problems. Genomic studies have shown that some...

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Detalles Bibliográficos
Autores principales: Na, Insung, Dai, Huanqin, Li, Hantian, Gupta, Anvita, Kreda, David, Zhang, Powell, Chen, Xiangyin, Zhang, Lixin, Alterovitz, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636726/
https://www.ncbi.nlm.nih.gov/pubmed/34901481
http://dx.doi.org/10.1016/j.synbio.2021.11.006