Cargando…
Computational prediction and validation of specific EmbR binding site on PknH
Tuberculosis drug resistance continues to threaten global health but the underline molecular mechanisms are not clear. Ethambutol (EMB), one of the well-known first - line drugs in tuberculosis treatment is, unfortunately, not free from drug resistance problems. Genomic studies have shown that some...
Autores principales: | Na, Insung, Dai, Huanqin, Li, Hantian, Gupta, Anvita, Kreda, David, Zhang, Powell, Chen, Xiangyin, Zhang, Lixin, Alterovitz, Gil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636726/ https://www.ncbi.nlm.nih.gov/pubmed/34901481 http://dx.doi.org/10.1016/j.synbio.2021.11.006 |
Ejemplares similares
-
The Ser/Thr Kinase PknH Is Essential for Maintaining Heterocyst Pattern in the Cyanobacterium Anabaena sp. Strain PCC 7120
por: Fukushima, Shun-ichi, et al.
Publicado: (2018) -
Mutations Found in embCAB, embR, and ubiA Genes of Ethambutol-Sensitive and -Resistant Mycobacterium tuberculosis Clinical Isolates from China
por: Xu, Yuhui, et al.
Publicado: (2015) -
Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference
por: Mata, Elena, et al.
Publicado: (2020) -
EmbRS a new two-component system that inhibits biofilm formation and saves Rubrivivax gelatinosus from sinking
por: Steunou, Anne Soisig, et al.
Publicado: (2013) -
Mycobacterium tuberculosis Transcription Factor EmbR Regulates the Expression of Key Virulence Factors That Aid in Ex Vivo and In Vivo Survival
por: Kumar, Suresh, et al.
Publicado: (2022)