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Nucleus Type-Specific DNA Methylomics Reveals Epigenetic “Memory” of Prior Adaptation in Skeletal Muscle

Using a mouse model of conditional and inducible in vivo fluorescent myonuclear labeling (HSA-GFP), sorting purification of nuclei, low-input reduced representation bisulfite sequencing (RRBS), and a translatable and reversible model of exercise (progressive weighted wheel running, PoWeR), we provid...

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Detalles Bibliográficos
Autores principales: Wen, Yuan, Dungan, Cory M, Mobley, C Brooks, Valentino, Taylor, von Walden, Ferdinand, Murach, Kevin A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8636928/
https://www.ncbi.nlm.nih.gov/pubmed/34870208
http://dx.doi.org/10.1093/function/zqab038