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Hepatocyte polarity establishment and apical lumen formation are organized by Par3, Cdc42, and aPKC in conjunction with Lgl

Hepatocytes differ from columnar epithelial cells by their multipolar organization, which follows the initial formation of central lumen-sharing clusters of polarized cells as observed during liver development and regeneration. The molecular mechanism for hepatocyte polarity establishment, however,...

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Detalles Bibliográficos
Autores principales: Tocan, Vlad, Hayase, Junya, Kamakura, Sachiko, Kohda, Akira, Ohga, Shouichi, Kohjima, Motoyuki, Sumimoto, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637150/
https://www.ncbi.nlm.nih.gov/pubmed/34717957
http://dx.doi.org/10.1016/j.jbc.2021.101354