USP18 and USP20 restrict oHSV-1 replication in resistant human oral squamous carcinoma cell line SCC9 and affect the viability of SCC9 cells

In this study, we discovered that two human oral squamous carcinoma cell (OSCC) lines, SCC9 and SCC25, exhibited varied levels of permissivity to oncolytic HSV-1 T1012G replication and the differential virus yields may associate with the constitutive accumulation of two deubiquitinating enzymes USP1...

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Detalles Bibliográficos
Autores principales: Lu, Ruitao, Wu, Guangxian, Chen, Meiling, Ji, Dongmei, Liu, Yonghong, Zhou, Grace Guoying, Fu, Wenmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637187/
https://www.ncbi.nlm.nih.gov/pubmed/34901390
http://dx.doi.org/10.1016/j.omto.2021.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637187/
https://www.ncbi.nlm.nih.gov/pubmed/34901390
http://dx.doi.org/10.1016/j.omto.2021.11.004

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