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Combination of Tumor Mutational Burden and Specific Gene Mutations Stratifies Outcome to Immunotherapy Across Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma

Purpose: To investigate the prognostic significance of tumor mutational burden (TMB) combined with specific prognosis-related gene mutations in immunotherapy for recurrent and metastatic head and neck squamous cell carcinoma (r/m HNSCC). Methods: One hundred thirty-two r/m HNSCC patients from the Mo...

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Detalles Bibliográficos
Autores principales: Peng, Ying-Peng, Wang, Rong, Liu, Qiao-Dan, Xu, Xi-Wei, Wei, Wei, Huang, Xiao-Tao, Peng, Xiao-Mou, Liu, Zhi-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637214/
https://www.ncbi.nlm.nih.gov/pubmed/34868231
http://dx.doi.org/10.3389/fgene.2021.756506