ATG4B Inhibitor UAMC-2526 Potentiates the Chemotherapeutic Effect of Gemcitabine in a Panc02 Mouse Model of Pancreatic Ductal Adenocarcinoma

Resistance against anti-cancer therapy is one of the major challenges during treatment of multiple cancers. Gemcitabine is a standard first-line chemotherapeutic drug, yet autophagy is highly activated in the hypoxic microenvironment of solid tumors and enhances the survival of tumor cells against g...

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Detalles Bibliográficos
Autores principales: Takhsha, Farnaz Sedigheh, Vangestel, Christel, Tanc, Muhammet, De Bruycker, Sven, Berg, Maya, Pintelon, Isabel, Stroobants, Sigrid, De Meyer, Guido R. Y., Van Der Veken, Pieter, Martinet, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637338/
https://www.ncbi.nlm.nih.gov/pubmed/34868951
http://dx.doi.org/10.3389/fonc.2021.750259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637338/
https://www.ncbi.nlm.nih.gov/pubmed/34868951
http://dx.doi.org/10.3389/fonc.2021.750259

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