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Targeted and activatable nanosystem for fluorescent and optoacoustic imaging of immune-mediated inflammatory diseases and therapy via inhibiting NF-κB/NLRP3 pathways

Immune-mediated inflammatory diseases (IMIDs) represent a diverse group of diseases and challenges remain for the current medications. Herein, we present an activatable and targeted nanosystem for detecting and imaging IMIDs foci and treating them through blocking NF-κB/NLRP3 pathways. A ROS-activat...

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Detalles Bibliográficos
Autores principales: Sun, Lihe, Ouyang, Juan, Zeng, Zhuo, Zeng, Cheng, Ma, Yunqing, Zeng, Fang, Wu, Shuizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637343/
https://www.ncbi.nlm.nih.gov/pubmed/34901531
http://dx.doi.org/10.1016/j.bioactmat.2021.08.010