Neuron Type-Dependent Synaptic Activity in the Spinal Dorsal Horn of Opioid-Induced Hyperalgesia Mouse Model

Opioids are widely used for pain relief; however, chronic opioid use causes a paradoxical state of enhanced pain sensitivity, termed “Opioid-induced hyperalgesia (OIH).” Despite the clinical importance of OIH, the detailed mechanism by which it enhances pain sensitivity remains unclear. In this stud...

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Detalles Bibliográficos
Autores principales: Kearns, Austin, Jayasi, Jazmine, Liu, Xin, Wang, Jigong, Shi, Yuqiang, Chung, Jin Mo, La, Jun-Ho, Tang, Shao-Jun, Bae, Chilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Synaptic Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637419/
https://www.ncbi.nlm.nih.gov/pubmed/34867259
http://dx.doi.org/10.3389/fnsyn.2021.748929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637419/
https://www.ncbi.nlm.nih.gov/pubmed/34867259
http://dx.doi.org/10.3389/fnsyn.2021.748929

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