Cargando…

Neuron Type-Dependent Synaptic Activity in the Spinal Dorsal Horn of Opioid-Induced Hyperalgesia Mouse Model

Opioids are widely used for pain relief; however, chronic opioid use causes a paradoxical state of enhanced pain sensitivity, termed “Opioid-induced hyperalgesia (OIH).” Despite the clinical importance of OIH, the detailed mechanism by which it enhances pain sensitivity remains unclear. In this stud...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kearns, Austin, Jayasi, Jazmine, Liu, Xin, Wang, Jigong, Shi, Yuqiang, Chung, Jin Mo, La, Jun-Ho, Tang, Shao-Jun, Bae, Chilman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Synaptic Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637419/ https://www.ncbi.nlm.nih.gov/pubmed/34867259 http://dx.doi.org/10.3389/fnsyn.2021.748929

Ejemplares similares

Mitochondrial superoxide increases excitatory synaptic strength in spinal dorsal horn neurons of neuropathic mice
por: Bae, Chilman, et al.
Publicado: (2018)

Distribution of delta and mu opioid receptor mRNA in rodent dorsal root ganglia neurons
por: Quirion, Béatrice, et al.
Publicado: (2022)

Differential involvement of reactive oxygen species in a mouse model of capsaicin-induced secondary mechanical hyperalgesia and allodynia
por: La, Jun-Ho, et al.
Publicado: (2017)

Intrinsic subthreshold oscillations extend the influence of inhibitory synaptic inputs on cortical pyramidal neurons
por: Stiefel, Klaus M, et al.
Publicado: (2010)

Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure
por: Díaz González, Marta, et al.
Publicado: (2021)

Crosstalk between Activated Microglia and Neurons in the Spinal Dorsal Horn Contributes to Stress-induced Hyperalgesia
por: Qi, Jian, et al.
Publicado: (2016)

Role of P2X4 receptors in synaptic strengthening in mouse CA1 hippocampal neurons
por: Baxter, Andrew W, et al.
Publicado: (2011)

Inflammation condition sensitizes Piezo1 mechanosensitive channel in mouse cerebellum astrocyte
por: Yu, Donggyeom, et al.
Publicado: (2023)

μ-Opioid receptor desensitization: homologous or heterologous?
por: Llorente, Javier, et al.
Publicado: (2012)

Role of protein kinase C and μ-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons
por: Bailey, C P, et al.
Publicado: (2009)

Fetal Neuroprotective Strategies: Therapeutic Agents and Their Underlying Synaptic Pathways
por: Elsayed, Nada A., et al.
Publicado: (2021)

Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity
por: Barber, Casey N., et al.
Publicado: (2022)

MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex
por: Scott, Helen L, et al.
Publicado: (2012)

Normalizing JMJD6 Expression in Rat Spinal Dorsal Horn Alleviates Hyperalgesia Following Chronic Constriction Injury
por: Mo, Cheng, et al.
Publicado: (2018)

Effects of the clathrin inhibitor Pitstop-2 on synaptic vesicle recycling at a central synapse in vivo
por: Paksoy, Alp, et al.
Publicado: (2022)

Pain-related synaptic plasticity in spinal dorsal horn neurons: role of CGRP
por: Bird, Gary C, et al.
Publicado: (2006)

Morphological, biophysical and synaptic properties of glutamatergic neurons of the mouse spinal dorsal horn
por: Punnakkal, Pradeep, et al.
Publicado: (2014)

Synaptic Targets of Glycinergic Neurons in Laminae I–III of the Spinal Dorsal Horn
por: Miranda, Camila Oliveira, et al.
Publicado: (2023)

Electroacupuncture relieves hyperalgesia by regulating neuronal–glial interaction and glutamate transporters of spinal dorsal horns in rats with acute incisional neck pain
por: Wang, Jun-ying, et al.
Publicado: (2022)

The effect of µ-opioid receptor activation on GABAergic neurons in the spinal dorsal horn
por: Kim, Yoo Rim, et al.
Publicado: (2018)

Deletion of ErbB4 Disrupts Synaptic Transmission and Long-Term Potentiation of Thalamic Input to Amygdalar Medial Paracapsular Intercalated Cells
por: Asede, Douglas, et al.
Publicado: (2021)

Chemokine CCL2 prevents opioid-induced inhibition of nociceptive synaptic transmission in spinal cord dorsal horn
por: Heles, Mario, et al.
Publicado: (2021)

Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes
por: Zhang, Haijun, et al.
Publicado: (2009)

Myelinated, synapsing cultures of murine spinal cord – validation as an in vitro model of the central nervous system
por: Thomson, C E, et al.
Publicado: (2008)

Identification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neurons
por: Dahlström, Märta, et al.
Publicado: (2019)

Dissociation of μ- and δ-opioid inhibition of glutamatergic synaptic transmission in superficial dorsal horn
por: Wrigley, Paul J, et al.
Publicado: (2010)

Modulation of GABAergic Synaptic Transmission by NMDA Receptors in the Dorsal Horn of the Spinal Cord
por: Leonardon, Benjamin, et al.
Publicado: (2022)

Mechanisms regulating spill‐over of synaptic glutamate to extrasynaptic NMDA receptors in mouse substantia nigra dopaminergic neurons
por: Wild, A. R., et al.
Publicado: (2015)

The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn
por: Abraira, Victoria E., et al.
Publicado: (2017)

Reactive Oxygen Species Donors Increase the Responsiveness of Dorsal Horn Neurons and Induce Mechanical Hyperalgesia in Rats
por: Kim, Hee Young, et al.
Publicado: (2015)

M-type channels selectively control bursting in rat dopaminergic neurons
por: Drion, Guillaume, et al.
Publicado: (2010)

Expression of cholecystokinin by neurons in mouse spinal dorsal horn
por: Gutierrez‐Mecinas, Maria, et al.
Publicado: (2019)

Effect of Unilateral Acoustic Trauma on Neuronal Firing Activity in the Inferior Colliculus of Mice
por: Hsiao, Chun-Jen, et al.
Publicado: (2021)

Cell‐type‐specific visualisation and biochemical isolation of endogenous synaptic proteins in mice
por: Zhu, Fei, et al.
Publicado: (2019)

Decoding glutamate receptor activation by the Ca(2+) sensor protein hippocalcin in rat hippocampal neurons
por: Dovgan, A V, et al.
Publicado: (2010)

Non-neuronal, slow GABA signalling in the ventrobasal thalamus targets δ-subunit-containing GABA(A) receptors
por: Jiménez-González, Cristina, et al.
Publicado: (2011)

Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse
por: Allichon, Marie-Charlotte, et al.
Publicado: (2021)

Distinct forms of synaptic inhibition and neuromodulation regulate calretinin-positive neuron excitability in the spinal cord dorsal horn
por: Smith, K.M., et al.
Publicado: (2016)

Enhanced inhibitory synaptic transmission in the spinal dorsal horn mediates antinociceptive effects of TC-2559
por: Cheng, Long-Zhen, et al.
Publicado: (2011)

Anti-allodynic and promotive effect on inhibitory synaptic transmission of riluzole in rat spinal dorsal horn
por: Taiji, Ryo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qhjcnsrcr0o4u5fur22i1timui