Cargando…

TGFβ Signaling in Myeloid Cells Promotes Lung and Liver Metastasis Through Different Mechanisms

TGFβ overexpression is commonly detected in cancer patients and correlates with poor prognosis and metastasis. Cancer progression is often associated with an enhanced recruitment of myeloid-derived cells to the tumor microenvironment. Here we show that functional TGFβ-signaling in myeloid cells is r...

Descripción completa

Detalles Bibliográficos
Autores principales: Stefanescu, Cristina, Van Gogh, Merel, Roblek, Marko, Heikenwalder, Mathias, Borsig, Lubor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637420/
https://www.ncbi.nlm.nih.gov/pubmed/34868988
http://dx.doi.org/10.3389/fonc.2021.765151