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TGFβ Signaling in Myeloid Cells Promotes Lung and Liver Metastasis Through Different Mechanisms
TGFβ overexpression is commonly detected in cancer patients and correlates with poor prognosis and metastasis. Cancer progression is often associated with an enhanced recruitment of myeloid-derived cells to the tumor microenvironment. Here we show that functional TGFβ-signaling in myeloid cells is r...
Autores principales: | Stefanescu, Cristina, Van Gogh, Merel, Roblek, Marko, Heikenwalder, Mathias, Borsig, Lubor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637420/ https://www.ncbi.nlm.nih.gov/pubmed/34868988 http://dx.doi.org/10.3389/fonc.2021.765151 |
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