Repurposing Combination Therapy of Voacamine With Vincristine for Downregulation of Hypoxia-Inducible Factor-1α/Fatty Acid Synthase Co-axis and Prolyl Hydroxylase-2 Activation in ER+ Mammary Neoplasia

The current study investigated the role of combination therapy with voacamine and vincristine in preventing mammary gland carcinoma through prolyl hydroxylase-2 activation. Prolyl hydroxylase-2 activation leads to the downregulation of hypoxia-inducible factor-1α and fatty acid synthase. Overexpress...

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Detalles Bibliográficos
Autores principales: Singh, Lakhveer, Roy, Subhadeep, Kumar, Anurag, Rastogi, Shubham, Kumar, Dinesh, Ansari, Mohd. Nazam, Saeedan, Abdulaziz S., Singh, Manjari, Kaithwas, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637442/
https://www.ncbi.nlm.nih.gov/pubmed/34869321
http://dx.doi.org/10.3389/fcell.2021.736910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637442/
https://www.ncbi.nlm.nih.gov/pubmed/34869321
http://dx.doi.org/10.3389/fcell.2021.736910

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