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Synthesis, stability, and cellular uptake of (131)I-estradiol against MCF7 and T-47D human cell lines as a radioligand for binding assay
Estradiol is a steroid hormone that works as an agonist estrogen receptor (ER). This compound is widely used as a ligand and bind specifically to the ERα. Radioligand binding assay is an in vitro method for drug development from natural products by synthesizing estradiol through radiolabeling using...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637476/ https://www.ncbi.nlm.nih.gov/pubmed/34901495 http://dx.doi.org/10.1016/j.heliyon.2021.e08438 |