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Synthesis, stability, and cellular uptake of (131)I-estradiol against MCF7 and T-47D human cell lines as a radioligand for binding assay

Estradiol is a steroid hormone that works as an agonist estrogen receptor (ER). This compound is widely used as a ligand and bind specifically to the ERα. Radioligand binding assay is an in vitro method for drug development from natural products by synthesizing estradiol through radiolabeling using...

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Detalles Bibliográficos
Autores principales: Daruwati, Isti, Gwiharto, Abednego Kristande, Kurniawan, Ahmad, Mahendra, Isa, Achmad, Tri Hanggono, Syaifudin, Mukh, Muchtaridi, Muchtaridi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637476/
https://www.ncbi.nlm.nih.gov/pubmed/34901495
http://dx.doi.org/10.1016/j.heliyon.2021.e08438