BRCA1 promoter hypermethylation on circulating tumor DNA correlates with improved survival of patients with ovarian cancer

Methylation of the BRCA1 promoter is an epigenetic gene expression regulator and is frequently observed in ovarian cancer; however, conversion of methylation status is thought to drive disease recurrence. Therefore, longitudinal monitoring of methylation status by liquid biopsy in cell‐free DNA may...

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Detalles Bibliográficos
Autores principales: Elazezy, Maha, Prieske, Katharina, Kluwe, Lan, Oliveira‐Ferrer, Leticia, Peine, Sven, Müller, Volkmar, Woelber, Linn, Schmalfeldt, Barbara, Pantel, Klaus, Joosse, Simon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637552/
https://www.ncbi.nlm.nih.gov/pubmed/34601813
http://dx.doi.org/10.1002/1878-0261.13108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637552/
https://www.ncbi.nlm.nih.gov/pubmed/34601813
http://dx.doi.org/10.1002/1878-0261.13108

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