Cargando…
Elesclomol induces copper‐dependent ferroptosis in colorectal cancer cells via degradation of ATP7A
Cancer cells reprogram their copper metabolism to adapt to adverse microenvironments, such as oxidative stress. The copper chelator elesclomol has been reported to have considerable anticancer efficacy, but the underlying mechanisms remain largely unknown. In this study, we found that elesclomol‐med...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637554/ https://www.ncbi.nlm.nih.gov/pubmed/34390123 http://dx.doi.org/10.1002/1878-0261.13079 |