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Human intestinal and circulating invariant natural killer T cells are cytotoxic against colorectal cancer cells via the perforin–granzyme pathway

Invariant natural killer T (iNKT) cells are lipid‐specific T lymphocytes endowed with cytotoxic activities and are thus considered important in antitumor immunity. While several studies have demonstrated iNKT cell cytotoxicity against different tumors, very little is known about their cell‐killing a...

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Detalles Bibliográficos
Autores principales: Díaz‐Basabe, Angélica, Burrello, Claudia, Lattanzi, Georgia, Botti, Fiorenzo, Carrara, Alberto, Cassinotti, Elisa, Caprioli, Flavio, Facciotti, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637555/
https://www.ncbi.nlm.nih.gov/pubmed/34535957
http://dx.doi.org/10.1002/1878-0261.13104