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Genomic analyses of high‐grade neuroendocrine gynecological malignancies reveal a unique mutational landscape and therapeutic vulnerabilities

High‐grade neuroendocrine carcinoma of gynecologic origin (NEC‐GYN) is a highly aggressive cancer that often affects young women. The clinical management of NEC‐GYN is typically extrapolated from its counterpart, small cell carcinoma of the lung (SCLC), but, unfortunately, available therapies have l...

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Detalles Bibliográficos
Autores principales: Mahdi, Haider, Joehlin‐Price, Amy, Elishaev, Esther, Dowlati, Afshin, Abbas, Ata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637558/
https://www.ncbi.nlm.nih.gov/pubmed/34245124
http://dx.doi.org/10.1002/1878-0261.13057