Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells

Late‐stage colorectal cancer (CRC) is still a clinically challenging problem. The activity of the tumor suppressor p53 is regulated via post‐translational modifications (PTMs). While the relevance of p53 C‐terminal acetylation for transcriptional regulation is well defined, it is unknown whether thi...

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Detalles Bibliográficos
Autores principales: Marx, Christian, Sonnemann, Jürgen, Beyer, Mandy, Maddocks, Oliver D. K., Lilla, Sergio, Hauzenberger, Irene, Piée‐Staffa, Andrea, Siniuk, Kanstantsin, Nunna, Suneetha, Marx‐Blümel, Lisa, Westermann, Martin, Wagner, Tobias, Meyer, Felix B., Thierbach, René, Mullins, Christina S., Kdimati, Said, Linnebacher, Michael, Neri, Francesco, Heinzel, Thorsten, Wang, Zhao‐Qi, Krämer, Oliver H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637561/
https://www.ncbi.nlm.nih.gov/pubmed/34258881
http://dx.doi.org/10.1002/1878-0261.13060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637561/
https://www.ncbi.nlm.nih.gov/pubmed/34258881
http://dx.doi.org/10.1002/1878-0261.13060

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