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Molecular characteristics and tumorigenicity of ascites‐derived tumor cells: mitochondrial oxidative phosphorylation as a novel therapy target in ovarian cancer

Ovarian cancer disseminates primarily intraperitoneally. Detached tumor cell aggregates (spheroids) from the primary tumor are regarded as ‘metastatic units’ that exhibit a low sensitivity to classical chemotherapy, probably due to their unique molecular characteristics. We have analyzed the cellula...

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Detalles Bibliográficos
Autores principales: Ding, Yi, Labitzky, Vera, Legler, Karen, Qi, Minyue, Schumacher, Udo, Schmalfeldt, Barbara, Stürken, Christine, Oliveira‐Ferrer, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637562/
https://www.ncbi.nlm.nih.gov/pubmed/34060699
http://dx.doi.org/10.1002/1878-0261.13028