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Molecular characteristics and tumorigenicity of ascites‐derived tumor cells: mitochondrial oxidative phosphorylation as a novel therapy target in ovarian cancer
Ovarian cancer disseminates primarily intraperitoneally. Detached tumor cell aggregates (spheroids) from the primary tumor are regarded as ‘metastatic units’ that exhibit a low sensitivity to classical chemotherapy, probably due to their unique molecular characteristics. We have analyzed the cellula...
Autores principales: | Ding, Yi, Labitzky, Vera, Legler, Karen, Qi, Minyue, Schumacher, Udo, Schmalfeldt, Barbara, Stürken, Christine, Oliveira‐Ferrer, Leticia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637562/ https://www.ncbi.nlm.nih.gov/pubmed/34060699 http://dx.doi.org/10.1002/1878-0261.13028 |
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