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Immune modulation underpins the anti‐cancer activity of HDAC inhibitors

Aberrant protein acetylation is strongly linked to tumorigenesis, and modulating acetylation through targeting histone deacetylase (HDAC) with small‐molecule inhibitors has been the focus of clinical trials. However, clinical success on solid tumours, such as colorectal cancer (CRC), has been limite...

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Detalles Bibliográficos
Autores principales: Blaszczak, Wiktoria, Liu, Geng, Zhu, Hong, Barczak, Wojciech, Shrestha, Amit, Albayrak, Gulsah, Zheng, Shunsheng, Kerr, David, Samsonova, Anastasia, La Thangue, Nicholas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637571/
https://www.ncbi.nlm.nih.gov/pubmed/33773029
http://dx.doi.org/10.1002/1878-0261.12953