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Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia‐inducible factor‐1α in colorectal cancer

Distant metastasis is a major cause of death in patients with colorectal cancer (CRC) but the management of advanced and metastatic CRC still remains problematic due to the distinct molecular alterations during tumor progression. Tumor angiogenesis is a key step in tumor growth, invasion and metasta...

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Detalles Bibliográficos
Autores principales: Fang, Chao, Dai, Lei, Wang, Cun, Fan, Chuanwen, Yu, Yongyang, Yang, Lie, Deng, Hongxin, Zhou, Zongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637574/
https://www.ncbi.nlm.nih.gov/pubmed/34160138
http://dx.doi.org/10.1002/1878-0261.13044