The lncRNA ‘UCA1’ modulates the response to chemotherapy of ovarian cancer through direct binding to miR‐27a‐5p and control of UBE2N levels

Ovarian cancer (OC) is the leading cause of death in patients with gynecologic cancers. Due to late diagnosis and resistance to chemotherapy, the 5‐year survival rate in patients with OC is below 40%. We observed that UCA1, a lncRNA previously reported to play an oncogenic role in several malignanci...

Descripción completa

Detalles Bibliográficos
Autores principales: Wambecke, Anaïs, Ahmad, Mohammad, Morice, Pierre‐Marie, Lambert, Bernard, Weiswald, Louis‐Bastien, Vernon, Mégane, Vigneron, Nicolas, Abeilard, Edwige, Brotin, Emilie, Figeac, Martin, Gauduchon, Pascal, Poulain, Laurent, Denoyelle, Christophe, Meryet‐Figuiere, Matthieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637575/
https://www.ncbi.nlm.nih.gov/pubmed/34160887
http://dx.doi.org/10.1002/1878-0261.13045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637575/
https://www.ncbi.nlm.nih.gov/pubmed/34160887
http://dx.doi.org/10.1002/1878-0261.13045

Ejemplares similares