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Proteolysis of Amyloid β by Lysosomal Enzymes as a Function of Fibril Morphology

[Image: see text] Aggregation of amyloid-β (Aβ) into extracellular plaques is a well-known hallmark of Alzheimer’s disease (AD). Similarly, autophagic vacuoles, autophagosomes, and other residual bodies within dystrophic neurites, though more difficult to detect, are characteristic features of AD. T...

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Detalles Bibliográficos
Autores principales: Lambeth, Tyler R., Julian, Ryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637590/
https://www.ncbi.nlm.nih.gov/pubmed/34869978
http://dx.doi.org/10.1021/acsomega.1c03915