Construction of Spirooxindole Analogues Engrafted with Indole and Pyrazole Scaffolds as Acetylcholinesterase Inhibitors

[Image: see text] Twenty-five new hits of spirooxindole analogs 8a–y engrafted with indole and pyrazole scaffolds were designed and constructed via a [3+2]cycloaddition (32CA) reaction starting from three components: new chalcone-based indole and pyrazole scaffolds 5a–d, substituted isatins 6a–c, an...

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Detalles Bibliográficos
Autores principales: Islam, Mohammad Shahidul, Al-Majid, Abdullah Mohammed, Azam, Mohammad, Verma, Ved Prakash, Barakat, Assem, Haukka, Matti, Elgazar, Abdullah A., Mira, Amira, Badria, Farid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637602/
https://www.ncbi.nlm.nih.gov/pubmed/34869980
http://dx.doi.org/10.1021/acsomega.1c03978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637602/
https://www.ncbi.nlm.nih.gov/pubmed/34869980
http://dx.doi.org/10.1021/acsomega.1c03978

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