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Neuroprotection by dipeptidyl-peptidase-4 inhibitors and glucagon-like peptide-1 analogs via the modulation of AKT-signaling pathway in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common reason for progressive dementia in the elderly. It has been shown that disorders of the mammalian/mechanistic target of rapamycin (mTOR) signaling pathways are related to the AD. On the other hand, diabetes mellitus (DM) is a risk factor for the cognitive...

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Detalles Bibliográficos
Autores principales: Ikeda, Yuka, Nagase, Nozomi, Tsuji, Ai, Kitagishi, Yasuko, Matsuda, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637616/
https://www.ncbi.nlm.nih.gov/pubmed/34904048
http://dx.doi.org/10.4331/wjbc.v12.i6.104