Cargando…

Neuroprotection by dipeptidyl-peptidase-4 inhibitors and glucagon-like peptide-1 analogs via the modulation of AKT-signaling pathway in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common reason for progressive dementia in the elderly. It has been shown that disorders of the mammalian/mechanistic target of rapamycin (mTOR) signaling pathways are related to the AD. On the other hand, diabetes mellitus (DM) is a risk factor for the cognitive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ikeda, Yuka, Nagase, Nozomi, Tsuji, Ai, Kitagishi, Yasuko, Matsuda, Satoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2021
Materias:	Minireviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637616/ https://www.ncbi.nlm.nih.gov/pubmed/34904048 http://dx.doi.org/10.4331/wjbc.v12.i6.104

Ejemplares similares

Efficacy of probiotics on the modulation of gut microbiota in the treatment of diabetic nephropathy
por: Nagase, Nozomi, et al.
Publicado: (2022)

Special bioactive compounds and functional foods may exhibit neuroprotective effects in patients with dementia (Review)
por: Murakami, Mutsumi, et al.
Publicado: (2020)

Roles of PI3K/AKT/GSK3 Pathway Involved in Psychiatric Illnesses
por: Matsuda, Satoru, et al.
Publicado: (2019)

Role of dipeptidyl peptidase 4 inhibitors in the new era of antidiabetic treatment
por: Florentin, Matilda, et al.
Publicado: (2022)

Dipeptidyl peptidase 4 inhibitors in COVID-19: Beyond glycemic control
por: Narayanan, Niya, et al.
Publicado: (2022)

Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute to neuroprotection in a traumatic brain injury
por: Kitagishi, Yasuko, et al.
Publicado: (2013)

Implications of PI3K/AKT/PTEN Signaling on Superoxide Dismutases Expression and in the Pathogenesis of Alzheimer’s Disease
por: Matsuda, Satoru, et al.
Publicado: (2018)

d‐Leucine protects oocytes from chronic psychological stress in mice
por: Tsuji, Ai, et al.
Publicado: (2021)

Reduction of oocyte lipid droplets and meiotic failure due to biotin deficiency was not rescued by restoring the biotin nutritional status
por: Tsuji, Ai, et al.
Publicado: (2022)

Repositioning of dipeptidyl peptidase-4 inhibitors and glucagon like peptide-1 agonists as potential neuroprotective agents
por: Mousa, Shaker A., et al.
Publicado: (2019)

By using either endogenous or transplanted stem cells, which could you prefer for neural regeneration?
por: Matsuda, Satoru, et al.
Publicado: (2018)

Role of tumor suppressor molecules in genomic perturbations and damaged DNA repair involved in the pathogenesis of cancer and neurodegeneration (Review)
por: Matsuda, Satoru, et al.
Publicado: (2020)

Diet induces hepatocyte protection in fatty liver disease via modulation of PTEN signaling
por: Ikeda, Yuka, et al.
Publicado: (2020)

D-Amino Acids as a Biomarker in Schizophrenia
por: Taniguchi, Kurumi, et al.
Publicado: (2022)

Acute hemodynamic and renal effects of glucagon-like peptide 1 analog and dipeptidyl peptidase-4 inhibitor in rats
por: Zhou, Xiaoyan, et al.
Publicado: (2015)

Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease
por: Kitagishi, Yasuko, et al.
Publicado: (2014)

Roles for PI3K/AKT/PTEN Pathway in Cell Signaling of Nonalcoholic Fatty Liver Disease
por: Matsuda, Satoru, et al.
Publicado: (2013)

Roles of PI3K/AKT/PTEN Pathway as a Target for Pharmaceutical Therapy
por: Matsuda, Satoru, et al.
Publicado: (2013)

New insights into the role of dipeptidyl peptidase 8 and dipeptidyl peptidase 9 and their inhibitors
por: Cui, Chenkai, et al.
Publicado: (2022)

Roles of PI3K/AKT/GSK3/mTOR Pathway in Cell Signaling of Mental Illnesses
por: Kitagishi, Yasuko, et al.
Publicado: (2012)

Dipeptidyl peptidase IV inhibitors in diabetes: more than inhibition of glucagon-like peptide-1 metabolism?
por: Michel, Martin C., et al.
Publicado: (2008)

BRCA1 and p53 Tumor Suppressor Molecules in Alzheimer’s Disease
por: Nakanishi, Atsuko, et al.
Publicado: (2015)

A theoretical investigation on the geometries of glucagon-like peptide-1 and its interactions with dipeptidyl peptidase DPP-IV
por: Brickmann, Jürgen, et al.
Publicado: (2008)

Serum and Adipose Dipeptidyl Peptidase 4 in Cardiovascular Surgery Patients: Influence of Dipeptidyl Peptidase 4 Inhibitors
por: Shibasaki, Ikuko, et al.
Publicado: (2022)

RUFY, Rab and Rap Family Proteins Involved in a Regulation of Cell Polarity and Membrane Trafficking
por: Kitagishi, Yasuko, et al.
Publicado: (2013)

Peroxisome Proliferator-Activated Receptor and Vitamin D Receptor Signaling Pathways in Cancer Cells
por: Matsuda, Satoru, et al.
Publicado: (2013)

PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis
por: Okumura, Naoko, et al.
Publicado: (2012)

Evolutionary Analysis of Dipeptidyl Peptidase I
por: Varda, Nina, et al.
Publicado: (2022)

Reactive Oxygen Species, Superoxide Dimutases, and PTEN-p53-AKT-MDM2 Signaling Loop Network in Mesenchymal Stem/Stromal Cells Regulation
por: Matsuda, Satoru, et al.
Publicado: (2018)

Aminopeptidase A and dipeptidyl peptidase 4: a pathogenic duo in Alzheimer’s disease?
por: Checler, Frédéric, et al.
Publicado: (2022)

Dipeptidyl Peptidase-4 Inhibitor (Vildagliptin) Improves Glycemic Control After Meal Tolerance Test by Suppressing Glucagon Release
por: Okamoto, Aki, et al.
Publicado: (2014)

Dipeptidyl‐Peptidase 4 Inhibition and the Vascular Effects of Glucagon‐like Peptide‐1 and Brain Natriuretic Peptide in the Human Forearm
por: Devin, Jessica K., et al.
Publicado: (2014)

Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension
por: Wang, Jingjing, et al.
Publicado: (2019)

The Nonglycemic Actions of Dipeptidyl Peptidase-4 Inhibitors
por: Kim, Na-Hyung, et al.
Publicado: (2014)

Dipeptidyl peptidase-4 and kidney fibrosis in diabetes
por: Shi, Sen, et al.
Publicado: (2016)

Tackling dipeptidyl peptidase IV in neurological disorders
por: Al-Badri, Ghaith, et al.
Publicado: (2018)

Dipeptidyl Peptidase IV as a Muscle Myokine
por: Kluess, Heidi A.
Publicado: (2020)

Angioedema associated with dipeptidyl peptidase-IV inhibitors
por: Cassano, Nicoletta, et al.
Publicado: (2021)

Peptidases in human bronchoalveolar lining fluid, macrophages, and epithelial cells: Dipeptidyl (amino)peptidase IV, aminopeptidase N, and dipeptidyl (carboxy)peptidase (angiotensin-converting enzyme)()
por: Juillerat-Jeanneret, Lucienne, et al.
Publicado: (1997)

The role of renal dipeptidyl peptidase-4 in kidney disease: renal effects of dipeptidyl peptidase-4 inhibitors with a focus on linagliptin
por: Kanasaki, Keizo
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_oapqn01k9s8l1gqvg2ufl3dfm2