Bone morphogenetic protein 6–mediated crosstalk between endothelial cells and hepatocytes recapitulates the iron-sensing pathway in vitro

Liver sinusoidal endothelial cell–derived bone morphogenetic protein 6 (BMP6) and the BMP6–small mothers against decapentaplegic homolog (SMAD) signaling pathway are essential for the expression of hepcidin, the secretion of which is considered the systemic master switch of iron homeostasis. However...

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Detalles Bibliográficos
Autores principales: Wang, Shijin, Chen, Cheng, Yu, Linna, Mueller, Johannes, Rausch, Vanessa, Mueller, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637636/
https://www.ncbi.nlm.nih.gov/pubmed/34740612
http://dx.doi.org/10.1016/j.jbc.2021.101378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637636/
https://www.ncbi.nlm.nih.gov/pubmed/34740612
http://dx.doi.org/10.1016/j.jbc.2021.101378

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