Cargando…

Bone morphogenetic protein 6–mediated crosstalk between endothelial cells and hepatocytes recapitulates the iron-sensing pathway in vitro

Liver sinusoidal endothelial cell–derived bone morphogenetic protein 6 (BMP6) and the BMP6–small mothers against decapentaplegic homolog (SMAD) signaling pathway are essential for the expression of hepcidin, the secretion of which is considered the systemic master switch of iron homeostasis. However...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Shijin, Chen, Cheng, Yu, Linna, Mueller, Johannes, Rausch, Vanessa, Mueller, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637636/ https://www.ncbi.nlm.nih.gov/pubmed/34740612 http://dx.doi.org/10.1016/j.jbc.2021.101378

Ejemplares similares

Novel Insights into Alcoholic Liver Disease: Iron Overload, Iron Sensing and Hemolysis
por: Mueller, Sebastian, et al.
Publicado: (2022)

IL-1 beta-mediated macrophage-hepatocyte crosstalk upregulates hepcidin under physiological low oxygen levels
por: Silva, Inês, et al.
Publicado: (2019)

H(2)O(2)-mediated autophagy during ethanol metabolism
por: Chen, Cheng, et al.
Publicado: (2021)

Direct modulation of hepatocyte hepcidin signaling by iron
por: Yu, Lin-Na, et al.
Publicado: (2021)

Recapitulation of morphogenetic cell shape changes enables wound re-epithelialisation
por: Razzell, William, et al.
Publicado: (2014)

Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro
por: Mahli, Abdo, et al.
Publicado: (2019)

Does Hypoxia Cause Carcinogenic Iron Accumulation in Alcoholic Liver Disease (ALD)?
por: Silva, Inês, et al.
Publicado: (2017)

Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis
por: Core, Amanda B., et al.
Publicado: (2014)

Recapitulating the Angiogenic Switch in a Hydrogel-Based 3D In Vitro Tumor-Stroma Model
por: Kuehlbach, Claudia, et al.
Publicado: (2021)

Examining Crosstalk among Transforming Growth Factor β, Bone Morphogenetic Protein, and Wnt Pathways
por: Coster, Adam D., et al.
Publicado: (2017)

Bone morphogenetic protein and Notch signalling crosstalk in poor‐prognosis, mesenchymal‐subtype colorectal cancer
por: Irshad, Shazia, et al.
Publicado: (2017)

Loss of mismatch repair signaling impairs the WNT–bone morphogenetic protein crosstalk and the colonic homeostasis
por: Nørgaard, Katrine, et al.
Publicado: (2019)

Confounders of Serum Phosphatidylethanol: Role of Red Blood Cell Turnover and Cirrhosis
por: Bartel, Marc, et al.
Publicado: (2023)

Receptor oligomerization and beyond: a case study in bone morphogenetic proteins
por: Heinecke, Kai, et al.
Publicado: (2009)

Bone morphogenetic protein-binding endothelial regulator of liver sinusoidal endothelial cells induces iron overload in a fatty liver mouse model
por: Hasebe, Takumu, et al.
Publicado: (2016)

Bone Morphogenetic Protein 7 (BMP-7) Influences Tendon-Bone Integration In Vitro
por: Schwarting, Tim, et al.
Publicado: (2015)

Hypoxia enhances H(2)O(2)-mediated upregulation of hepcidin: Evidence for NOX4-mediated iron regulation
por: Silva, Inês, et al.
Publicado: (2018)

Bone Morphogenetic Protein 13 Has Protumorigenic Effects on Hepatocellular Carcinoma Cells In Vitro
por: Kersten, Vanessa, et al.
Publicado: (2023)

Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance
por: Mao, Hua, et al.
Publicado: (2021)

Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading
por: McDonald, Cameron J., et al.
Publicado: (2018)

“Do-it-yourself in vitro vasculature that recapitulates in vivo geometries for investigating endothelial-blood cell interactions”
por: Mannino, Robert G., et al.
Publicado: (2015)

Beyond osteogenesis: an in vitro comparison of the potentials of six bone morphogenetic proteins
por: Rivera, Jessica C., et al.
Publicado: (2013)

The Classic: Bone Morphogenetic Protein
por: Urist, Marshall R., et al.
Publicado: (2009)

The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells
por: Jiang, He, et al.
Publicado: (2016)

Bone morphogenetic protein-4 and bone morphogenetic protein receptors expressions in the adult rat eye
por: Maruyama-Koide, Yuka, et al.
Publicado: (2017)

In Vitro Recapitulation of Functional Microvessels for the Study of Endothelial Shear Response, Nitric Oxide and [Ca(2+)](i)
por: Li, Xiang, et al.
Publicado: (2015)

Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer
por: Steinert, Andre F, et al.
Publicado: (2009)

Effects of Osseointegration by Bone Morphogenetic Protein-2 on Titanium Implants In Vitro and In Vivo
por: Teng, Fu-Yuan, et al.
Publicado: (2016)

In Vitro Evaluation of Recombinant Bone Morphogenetic Protein-2 Bioactivity for Regenerative Medicine
por: Fung, Stephanie L., et al.
Publicado: (2019)

Bone Morphogenetic Protein 15 (BMP-15) Improves In Vitro Mouse Folliculogenesis
por: Jitjumnong, Jakree, et al.
Publicado: (2023)

Recapitulation
Publicado: (1866)

Nuclear variants of bone morphogenetic proteins
por: Felin, Jenny E, et al.
Publicado: (2010)

Bone Morphogenetic Proteins: Periodontal Regeneration
por: Rao, Subramaniam M, et al.
Publicado: (2013)

Bone morphogenetic protein guts it out
por: Leslie, Mitch
Publicado: (2013)

Bone morphogenetic proteins: The anomalous molecules
por: Jain, Aena Pundir, et al.
Publicado: (2013)

Bone Morphogenetic Proteins and Diabetic Retinopathy
por: Elmasry, Khaled, et al.
Publicado: (2021)

Three-dimensional in vitro modeling of malignant bone disease recapitulates experimentally accessible mechanisms of osteoinhibition
por: McNeill, Eoin P., et al.
Publicado: (2018)

Recapitulation of methotrexate hepatotoxicity with induced pluripotent stem cell-derived hepatocytes from patients with rheumatoid arthritis
por: Kim, Juryun, et al.
Publicado: (2018)

Rapid Recapitulation of Nonalcoholic Steatohepatitis upon Loss of Host Cell Factor 1 Function in Mouse Hepatocytes
por: Minocha, Shilpi, et al.
Publicado: (2019)

Hepatocyte Growth Factor Activator Inhibitor-1 Is Induced by Bone Morphogenetic Proteins and Regulates Proliferation and Cell Fate of Neural Progenitor Cells
por: Koivuniemi, Raili, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ka92ust344ditj95jtr6ct2u2e