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Target specificity of selective bioactive compounds in blocking α-dystroglycan receptor to suppress Lassa virus infection: an in silico approach

Lassa hemorrhagic fever, caused by Lassa mammarenavirus (LASV) infection, accumulates up to 5000 deaths every year. Currently, there is no vaccine available to combat this disease. In this study, a library of 200 bioactive compounds was virtually screened to study their drug-likeness with the capaci...

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Detalles Bibliográficos
Autores principales: Arefin, Adittya, Ismail Ema, Tanzila, Islam, Tamnia, Saddam Hossen, Md., Islam, Tariqul, Al Azad, Salauddin, Nasir Uddin Badal, Md., Aminul Islam, Md., Biswas, Partha, Alam, Nafee Ul, Islam, Enayetul, Anjum, Maliha, Masud, Afsana, Shaikh Kamran, Md., Rahman, Ahsab, Kumar Paul, Parag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637655/
https://www.ncbi.nlm.nih.gov/pubmed/34857680
http://dx.doi.org/10.7555/JBR.35.20210111